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2001 Technical Reports

The IGIPI Ontological Framework: Towards Integrating Gene Interactions with Protein Interactions

Bill Andreopoulos

Technical Report CS-2001-07

York University

December 2001

Abstract

Combining the results of different genomic and proteomic studies poses a problem for researchers, especially when such studies produce conflicting results. The IGIPI framework is an ontological framework that addresses the problem of combining data from multiple genomic experiments. IGIPI views different genomic experiments as pieces of a puzzle that if positioned properly will create a more complete model of the cell. IGIPI can also be used as an ontology-based clustering technique, to predict gene function more effectively than traditional clustering techniques.

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